Other Solvents
Medchemexpress LLC Carboplatin-d4 | 41575-94-4 | 99.0% | 375.28 | 1 MG
Carboplatin-d4 is the deuterium labeled Carboplatin. Carboplatin (NSC 241240) is a DNA synthesis inhibitor that binds to DNA, inhibits replication and transcription, and induces cell death. It is a derivative of CDDP and a potent anti-cancer agent. Deuterium substitution can affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Dimethyl fumarate-d2 | 23057-98-9 | 98.2% | 146.14 | 5 MG
Dimethyl fumarate-d2 is the deuterium labeled Dimethyl fumarate. Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Amitraz-d3 | 33089-61-1 | 99.5% | 5 MG
Amitraz-d3 is the deuterium labeled Amitraz. Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Sodium propionate-d5 | 202529-18-8 | 99.9% | 25 MG
Sodium propionate-d5 is the deuterium-labeled version of Sodium propionate, which is an orally active short-chain fatty acid. It is produced by intestinal bacteria from dietary fiber metabolism. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, reduces COX-2 expression and NO production, and induces Apoptosis and Autophagy. It also reduces HSV-1-induced keratitis and has anticancer effects against glioblastoma. Additionally, it exhibits neuroprotective, antioxidant, and anti-inflammatory activities, making it useful in research for spinal cord injury and Alzheimer's disease.
- Deuterium labeled compound.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC DL-Cystathionine-d4 | 146764-57-0 | 99.2% | 226.29 | 1 MG
DL-Cystathionine-d4 is the deuterium labeled DL-Cystathionine. It is a mixture of 4 isomers of cystathionine and allocystathionine. DL-Cystathionine is also an intermediate in the biosynthesis of the amino acid cysteine.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Roflumilast-d4 N-Oxide | 1794760-31-8 | C17H10D4Cl2F2N2O4 | 5 MG
Roflumilast-d4 N-Oxide is the deuterium labeled version of Roflumilast, a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively. It does not affect PDE1, PDE2, PDE3, or PDE5 isoenzymes from various cells. This compound is intended for research use only.
- Deuterium labeled version of roflumilast
- Selective PDE4 inhibitor
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Devimistat-d10 | 2586055-61-8 | C22H18D10O2S2 | 100 MG
Devimistat-d10 is the deuterium-labeled Devimistat. It is for research use only and not sold to patients. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium-labeled Devimistat
- For research use only
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Sildenafil-d8 | 951385-68-5 | C22H22D8N6O4S | 1 MG
Sildenafil-d8 is a deuterium-labeled form of Sildenafil, which is recognized as a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. The incorporation of stable heavy isotopes like deuterium into drug molecules is primarily for quantitative tracing during the drug development process. Deuteration can potentially influence the pharmacokinetic and metabolic characteristics of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Vitamin D3-d7 | 1627523-19-6 | C27H37D7O | 500 UG
Vitamin D3-d7 is a deuterium-labeled form of Vitamin D3 (Cholecalciferol), a naturally occurring vitamin known to induce cell differentiation and prevent the proliferation of cancer cells. It incorporates stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules, primarily as tracers for quantitation during drug development, with potential to influence pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Indole-d6 | 104959-27-5 | 123.18 | 10 MG
Indole-d6 is a deuterium-labeled indole and an endogenous metabolite. It is intended for research use only.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Store powder at -20°C for 3 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Diphenylmethanol-d5 | 95450-78-5 | 189.26 | 5 MG
Diphenylmethanol-d5 is a deuterium labeled Diphenylmethanol, for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer for quantitative analysis
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC 7-keto-Deoxycholic acid | 911-40-0 | 99.7% | 406.56 | 5 MG
7-keto-Deoxycholic acid is a metabolite of bile acids found in *Clostridium absonum*. It is also produced from *Lactobacillus* and *Bifidobacterium* under specific conditions. In vitro, its bioconversion rate increases with the addition of an equimolar concentration of deoxycholic acid. It is induced by deoxycholic acid and subsequently metabolized. For example, *E. lentum-like c-25* can convert cholic acid to deoxycholic acid and 7-keto-Deoxycholic acid under anaerobic incubation.
- Metabolite of bile acids.
- Can be converted from *Lactobacillus* and *Bifidobacterium*.
- Available in various quantities.
- High purity.
- Solid appearance, white to off-white color.
- Endogenous metabolite.
- Shipping at room temperature in continental US; storage at 4°C, protected from light.
- Soluble in DMSO.
Medchemexpress LLC L-glutamine-13C5,15N2,d5 | 2123439-02-9 | 99.9% | 158.13 | 13C5H5D515N2O3 | 10 MG
L-Glutamine-13C5,15N2,d5 is an isotopically labeled form of the amino acid L-glutamine containing five 13C atoms, two 15N atoms, and five deuterium atoms. Supplied as a 10 mg research pack, it is suitable for analytical and tracer applications such as mass spectrometry and NMR.
- Isotopically labeled with 13C, 15N, and deuterium for tracer studies.
- High isotopic and chemical purity for analytical workflows.
- Small 10 mg pack convenient for method development and limited-sample work.
- Solid form for accurate weighing and sample preparation.
- Compatible with mass spectrometry and NMR applications.
Medchemexpress LLC Posaconazole-d5 | 1217785-83-5 | 99.1% | 705.81 g/mol | C37H37D5F2N8O4 | 10 MG
Posaconazole-d5 is the deuterium-labeled analogue of posaconazole, provided as a high-purity stable isotope for use as an internal standard or tracer in analytical workflows. It is intended for quantitative method development and bioanalytical applications, supporting accurate quantitation in complex matrices when used with appropriate instrumentation and controls.
- High isotopic purity for reliable internal standard performance.
- Suitable for NMR, GC-MS, and LC-MS quantitative analysis.
- High chemical purity for reproducible analytical results.
- Available in small-mass vials convenient for trace-level experiments.
- Stable under recommended storage conditions to preserve integrity.